Alabama might be the favorite at -175, while LSU comes in at +150. Take the matchup between LSU and Alabama, for example. You can also bet on college football via the moneyline, meaning you’re betting on who will win the game outright. That makes for a push, and all money is given back like nothing ever happened. A lot of spreads will have a half-point at the end to make sure there is no tie for example, if the spread is -6, and the final margin of victory is six points. Alabama would have to win by over 6.5 points to cover their bet – which means seven or more – while LSU could lose by less than 6.5 points or win outright in order to win their end of the wager. Alabama might be favored by 6.5 points at home, so they would be -6.5, while LSU would be +6.5. You have a favorite and an underdog, so let’s say LSU and Alabama are playing. The most popular way to bet on college football is spread betting.